We have an online bookstore!!

Hi everyone!

We are pleased to inform you that we now have an online bookstore! Here we have listed some of the best books available for the MRCP, all the way from preparatory text books for the MRCP part 1 to clinical scenarios for PACES.

Click on the link below to access our bookstore!

Cardio4MRCP bookstore

Warm wishes

Cardio4MRCP team.

A question from our website

Q. The normal resting membrane potential of ventricular myocardium is

a. 85 to 90 mV
b. -85 to -90 mV
c. 70 to 80 mV
d. -70 to -80 mV
e. -30 to -40 mV





A. b. -85 to -90 mV

The resting membrane potential is corresponds to stage 4 of cardiac myocyte contraction. It is primarily due K+ channels. The resting membrane potential corresponds to diastole in cardiac contraction, and the normal potential is between -85 to -90 mV. When the myocyte is stimulated during the resting membrane potential, it results in influx of Na+ ions and the start of contraction.

As is seen in the above image, the cardiac action potential consists of 5 stage, beginning with phase 4 all the way back to phase 4.

Phase 4 - corresponds to resting membrane potential. K+ channels are open, and an electrolyte balance is achieved to maintain the potential between -85 to -95 mV

Phase 0 - This corresponds to the start of the action potential, and is due to rapid influx of Na+ ions and a rise in membrane potential. In essence, this is the depolarisation phase.

Phase 1 - The Na+ channels close, and the membrane potential reaches a plateau.

Phase 2 - The L-type Ca2+ channels open and calcium influx occurs. Outward movement of K+ starts in this phase.

Phase 3 - The Ca2+ channels close, and K+ efflux continues. This is the relaxation / repolarisation phase of the myocyte action potential.


For more questions like these, including various aspects of Cardiology for the MRCP part 1 exam, go to www.cardio4mrcp.com or click here.

Sales pitch!

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There ended the sales pitch! Sorry, had to be done.... :-)


Regards


Vik